Total 7064 patents for "2020-01-09"

TREATMENT OF PD-L1-POSITIVE MELANOMA USING AN ANTI-PD-1 ANTIBODY

Pub Date: 2020-01-09

Pub Number: US20200010549

The invention provides a method of treating a melanoma comprising (i) identifying a patient having a PD-L1 positive melanoma and (ii) administering to the patient an anti-PD-1 antibody or an antigen-binding portion thereof (an anti-PD-1 antibody monotherapy). The methods of the invention can extend progression-free survival for over 12 months and/or reduces the tumor size at least about 10%, about 20%, about 30%, about 40%, or about 50% compared to the tumor size prior to the administration.

HETEROPHASIC PROPYLENE POLYMER MATERIAL AND PROPYLENE-BASED RESIN COMPOSITION

Pub Date: 2020-01-09

Pub Number: US20200010599

A heterophasic propylene polymerization material, including a propylene polymer component (I) and an ethylene--olefin copolymer component (II), the heterophasic propylene polymerization material satisfying features (i) to (v): (i) the heterophasic propylene polymerization material contains a xylene-soluble content by 20 wt % or more; (ii) xylene-soluble content in the heterophasic propylene polymerization material has a limiting viscosity [] CXS not less than 5 dL/g; (iii) a melt flow rate of the propylene polymer component (I) is 70 g/10 min or more; (iv) MFR of the heterophasic propylene polymerization material is not less than 5 g/10 min; and (v) the number of gels of 100 m or more in diameter on a sheet for counting gels, including the heterophasic propylene polymerization material, is 1000 or less per 100 cm 2 of the sheet.

METHODS FOR IMPROVING COMPETENCY OF PLANT CELLS

Pub Date: 2020-01-09

Pub Number: US20200010838

The present invention provides methods for improving competency of plant cells for bacterial-mediated transformation comprising contacting the plant cells with an effective amount of polyethylene glycol (PEG) for a period of time prior to transformation. The ability to store and maintain competent plant cells for transformation and tissue culture allows more efficient planning and execution of large-scale experiments by providing flexibility of peak production hours, or during unplanned disruptions in the production process. These methods are useful in preserving the viability of plant cells in various storage conditions, thus improving their competency for transformation and tissue culture.

NETWORK SLICING SERVING FUNCTION

Pub Date: 2020-01-09

Pub Number: US20200015158

Techniques for implementing a network slice selection function are described. In one example aspect, a network slice instance request message is received for a user device. In response, the network slice selection function transmits a response message that includes information about allowed network slice instances for the user device. The allowed network slice instances include network slice instances that are available in the registration area of the user device.

Spacer Structure with High Plasma Resistance for Semiconductor Devices

Pub Date: 2020-01-09

Pub Number: US20200013872

Semiconductor device structures comprising a spacer feature having multiple spacer layers are provided. In one example, a semiconductor device includes an active area on a substrate, the active area comprising a source/drain region, a gate structure over the active area, the source/drain region being proximate the gate structure, a spacer feature having a first portion along a sidewall of the gate structure and having a second portion along the source/drain region, wherein the first portion of the spacer feature comprises a bulk spacer layer along the sidewall of the gate structure, wherein the second portion of the spacer feature comprises the bulk spacer layer and a treated seal spacer layer, the treated seal spacer layer being disposed along the source/drain region and between the bulk spacer layer and the source/drain region, and a contact etching stop layer on the spacer feature.

POSITION TRACKING SYSTEM AND METHOD USING RADIO SIGNALS AND INERTIAL SENSING

Pub Date: 2020-01-09

Pub Number: US20200011961

An RF position tracking system for wirelessly tracking the three-dimensional position of a tracked object. The tracked object has at least one mobile antenna and at least one inertial sensor. The system uses a plurality of base antennas which communicate with the mobile antenna using radio signals. The tracked object also incorporates the inertial sensor to improve position stability by allowing the system to compare position data from radio signals to data provided by the inertial sensor.

Electrostatic Trap Mass Spectrometer With Improved Ion Injection

Pub Date: 2020-01-09

Pub Number: US20200013601

A method of mass spectral analysis in an analytical electrostatic trap (14) is disclosed. The electrostatic trap (14) defines an electrostatic field volume and includes trap electrodes having static and non-ramped potentials. The method comprises injecting a continuous ion beam into the electrostatic field volume.

SURGICAL HANDLE ARTICULATION ASSEMBLY

Pub Date: 2020-01-09

Pub Number: US20200008801

The present disclosure includes apparatuses for a surgical handle assembly. An example apparatus includes a reloadable cartridge assembly and a surgical handle assembly including an articulation assembly configured to maintain the reloadable cartridge assembly in a first operation position, the articulation assembly comprising a knob in a first knob position coupled to a housing and a spring coupled to the housing configured to bias a sphere radially outward to a first slot of a radial position component.

GAMING DEVICE HAVING MULTIPLE GAME PLAY OPTION

Pub Date: 2020-01-09

Pub Number: US20200013262

Embodiments of this concept are directed to gaming devices that are configured to initiate multiple gaming events in response to a player input. The gaming device may include game initiating inputs that initiate a predetermined number of gaming events in response to the player input, or the gaming device may include configurable game initiating inputs that initiate a number of gaming events specified by the player, specified the gaming device, or specified by a gaming server. The gaming device or gaming server may set the number of initiated game events in response to the occurrence of a triggering event.

DIRECT MANIPULATION INTERFACE FOR DATA ANALYSIS

Pub Date: 2020-01-09

Pub Number: US20200012405

Implementations are described related to users directly manipulating visual depictions of aspects of a data set displayed in a user interface to generate or modify visual representations of the data set, such as a chart. The direct manipulation may be either through a computer input device, (e.g., a keyboard or mouse), or based on other input data, such as a touch input. Aspects of a data set include dimensions, which may be used to filter the data set, and metrics, which are quantifiable elements within the data set. In various implementations, input such as drag-and-drop operations corresponding to visual depictions of aspects of a data set may be interpreted in generating or modifying charts.

METHOD AND APPARATUS FOR ENCODING A VIDEO

Pub Date: 2020-01-09

Pub Number: US20200014915

A method and an apparatus for encoding a video are disclosed. For at least one block from a picture of said video, a first rate-distortion optimization is performed (602) for determining for a first splitting mode of said block into at least one first subblock, coding parameters of said at least one first subblock. At least one second rate-distortion optimization is performed (609) for determining for at least one second splitting mode of said block into at least one second subblock, coding parameters of said at least one second subblock. A best splitting mode for coding said block is determined (613) according to at least said first rate-distortion optimization and said second rate-distortion optimization, and said block is encoded (616) according to said best splitting mode. While performing (609) said at least one second rate-distortion optimization and when said at least one second subblock is located at a same position in the picture as said at least one first subblock and said at least one second subblock has a same width and same height as said at least one first subblock, at least one coding parameter of said at least one first subblock determined during said first rate-distortion optimization is used (605) for determining said coding parameters for said at least one second subblock.

POLYASPARTIC ESTER COMPOSITIONS, AND METHODS OF MAKING AND USING SAME

Pub Date: 2020-01-09

Pub Number: US20200010405

Methods of preparing a polyaspartic ester composition comprise reacting a primary diamine reactant composition with a diester reactant composition under conditions to prepare a polyaspartic ester composition having a primary amine value of less than 35 mg KOH/g wherein, at the time of the reaction, the combined water content of the primary diamine reactant composition and the diester reactant composition is less than 300 ppm. Compositions and methods of use of the compositions are also described.

SHEET, SHEET MANUFACTURING APPARATUS, AND SHEET MANUFACTURING METHOD

Pub Date: 2020-01-09

Pub Number: US20200011009

A sheet is configured to have a first complex having a fiber and a fiber aggregation inhibitor integrally, a second complex having a fiber and a fiber aggregation inhibitor integrally, and a binding material which combines the first complex and the second complex and contains a resin.

METHODS, APPARATUSES AND STORAGE MEDIUMS FOR ABLATION PLANNING AND PERFORMANCE

Pub Date: 2020-01-09

Pub Number: US20200008875

One or more devices, systems, methods and storage mediums for performing ablation planning and/or ablation performance are provided. Examples of applications for such devices, systems, methods and storage mediums include imaging, evaluating and diagnosing biological objects, such as, but not limited to, lesions and tumors, and such devices, systems, methods and storage mediums may be used for radiotherapy applications (e.g., to determine whether to place seed(s) for radiotherapy). Preferably, a medial axis or a center line for a predetermined biological object (e.g., a lesion or tumor) is determined/found, one or more target points are picked along the medial axis or center line, and the ablation or radiotherapy zones are defined and optimized. Security checks may be performed in one or more embodiments to ensure proper use of the equipment and patient information.

CUSHION FOR PATIENT INTERFACE

Pub Date: 2020-01-09

Pub Number: US20200009343

A cushion for a patient interface that delivers breathable gas to a patient includes a base wall structured to be connected to a frame, an underlying support cushion extending away from the base wall towards the patient's face in use, and a membrane provided to substantially cover at least a portion of the underlying cushion. The membrane is adapted to form a continuous seal on the patient's face. The underlying cushion has a spring-like connection with the base wall. The underlying cushion and/or base wall define a spring constant that varies along a length of the seal.

Finger Beam for Generating Haptic Feedback

Pub Date: 2020-01-09

Pub Number: US20200012345

According to some embodiments, a haptic feedback component is configured to generate haptic feedback in accordance with movement of a user. The haptic feedback component includes a frame having a size and shape for receiving an appendage of a user, a flexible beam member coupled to the frame, and a haptic feedback element that is coupled to the flexible beam member, wherein the haptic feedback element actuates in response to receiving an electrical signal so as to cause the flexible beam member to displace from an initial configuration to a modified configuration such as to direct the haptic feedback towards the appendage.

ROTOR OF ROTARY ELECTRIC MACHINE AND ROTARY ELECTRIC MACHINE

Pub Date: 2020-01-09

Pub Number: US20200014260

In a rotor, a permanent magnet 300 is an angulated pillar member of which the cross section perpendicular to the rotor shaft center is rectangular, and includes two pairs of facing side surfaces 310 to 340 which extend along the rotor shaft center, and the paired-up side surfaces 310 and 320 are provided such that one side surface is provided on a side near the rotor shaft center and the other one is provided on the outer peripheral side of the rotor. In the magnet storage slot 200A, a protruding portion 210 is provided which protrudes from an inner peripheral surface of the slot and abuts on a side surface 310 on a side near the rotor shaft center of any pair of side surfaces 310 and 320 in the two pairs. The protruding portion 210 applies, to the permanent magnet 300, an urging force F in which a component force F2 in the outer peripheral direction of the rotor along the abutting side surface 310 and a component force F1 in the outer peripheral direction of the rotor along the side surface 340 adjacent to the side surface 310 are not zero.

METHOD FOR EVALUATING BREAKAGE STRENGTH OF FIRST AND SECOND CEMENTED SURFACES OF WELL CEMENTATION UNDER DYNAMIC LOAD

Pub Date: 2020-01-09

Pub Number: US20200011777

A method for evaluating the breakage strength of first and second cemented surfaces of well cementation under a dynamic load, includes: producing a rock-set cement-casing composite structure sample; clamping the sample between an incident rod and an output rod of a Hopkinson rod, hitting the incident rod with a conical punch to generate incident waves, enabling the incident waves to pass through the sample to generate reflected waves and projected waves, recording dynamic strain signals of incident waves, reflected waves and projected waves, and converting the dynamic strain signals into electrical signals and transmitting the electrical signals to a computer; recording the process and the corresponding time point from breakage starting to a complete breakage of the first and second cemented surfaces by a photographic instrument; obtaining a strain rate time travel curve and a stress-strain curve, and obtaining the corresponding breakage strength by analyzing the curve peak points.

NOVEL IMMUNE STIMULATING COMPOUND

Pub Date: 2020-01-09

Pub Number: US20200010499

The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating intracellular bacterial, fungal, and protozoal infections.

DILATOR WITH SLIT AND SLIDABLE SLEEVE

Pub Date: 2020-01-09

Pub Number: US20200009359

The invention includes a dilator comprising a tube and an elastic, unitary sleeve that is slidable both longitudinally and transversely to the cylindrical barrel when disposed on the tube.

METHOD, APPARATUS, AND SYSTEM FOR REESTABLISHING RADIO COMMUNICATION LINKS DUE TO RADIO LINK FAILURE

Pub Date: 2020-01-09

Pub Number: US20200015310

One feature pertains to a method that includes establishing a radio communication connection with a first radio access node (RAN) that uses control plane signaling connections to carry user plane data. The method also includes determining that the wireless communication device is experiencing radio link failure (RLF) with the first RAN and that the radio communication connection should be reestablished with a second RAN. A reestablishment request message is transmitted to the second RAN that includes parameters that enable a core network node communicatively coupled to the second RAN to authenticate the wireless communication device and allow or reject reestablishment of the radio communication connection. The parameters include at least a message authentication code (MAC) based in part on one or more bits of a non-access stratum (NAS) COUNT value maintained at the wireless communication device.

SCALING EVENTS FOR HOSTING HIERARCHICAL DATA STRUCTURES

Pub Date: 2020-01-09

Pub Number: US20200012441

Scaling events may be detected for hosting hierarchical data structures. Scaling events may be detected to modify the capacity of a data store for hierarchical data structures to handle changing write workloads, read workloads, or storage capacity. Hierarchical data structures may be moved from one group of storage hosts to another group of storage hosts according to a filtered snapshot that includes the hierarchical data structures to be moved that is provided to the destination storage hosts. Changes made to the hierarchical data structures made at the source storage hosts during the move can be applied to the filtered snapshot so that the hierarchical data structures may be made available at the destination storage hosts inclusive of the changes.

DOPED PEROVSKITE HAVING IMPROVED STABILITY, AND SOLAR CELLS MADE THEREOF

Pub Date: 2020-01-09

Pub Number: US20200013973

A light-harvesting material comprises a perovskite absorber doped with a metal chalcogenide. The light-harvesting material may be used in a photovoltaic device, comprising (1) a first conductive layer, (2) an optional blocking layer, on the first conductive layer, (3) a semiconductor layer, on the first conductive layer, (4) a light-harvesting material, on the semiconductor layer, (5) a hole transport material, on the light-harvesting material, and (6) a second conductive layer, on the hole transport material.

Silicon Carbide Semiconductor Device Having a Metal Adhesion and Barrier Structure and a Method of Forming Such a Semiconductor Device

Pub Date: 2020-01-09

Pub Number: US20200013722

According to an embodiment of a semiconductor device, the semiconductor devices includes a metal structure electrically connected to a silicon carbide semiconductor body and a metal adhesion and barrier structure between the metal structure and the silicon carbide semiconductor body. The metal adhesion and barrier structure includes a layer comprising titanium and tungsten.

FOLDABLE ELECTRONIC DEVICE AND HINGE MECHANISM THEREOF

Pub Date: 2020-01-09

Pub Number: US20200012323

A hinge mechanism is provided, including a fixed member, a rotary member pivotally connected to the fixed member, a pin, a first gear set, and a second gear set. The first and second gear sets are connected to the fixed member and the rod and respectively have a teeth-uncompleted gear. When the rotary member rotates relative to the fixed member from an initial angle to a first angle, the first gear set drives the pin to rotate in a first direction. When the rotary member further rotates relative to the fixed member from the first angle to a second angle, the second gear set drives the ping to rotate in a second direction, which is the opposite of the first direction.

DRIVING ASSISTANCE APPARATUS AND DRIVING ASSISTANCE METHOD FOR VEHICLE

Pub Date: 2020-01-09

Pub Number: US20200010079

In a driving assistance apparatus, an object detecting unit detects an object that is present in a periphery of an own vehicle based on an image captured by an imaging apparatus provided in the own vehicle. An avoidance control unit performs collision avoidance control for avoiding a collision between the detected object and the own vehicle when a collision between the object and the own vehicle is likely. A light distribution control unit switches irradiated light of an irradiation apparatus provided in the own vehicle between high beam and low beam based on a predetermined switching condition. The light distribution control unit performs switching suppression control to suppress switching of the irradiated light from high beam to low beam while the avoidance control unit is performing collision avoidance control in a case where the irradiated light is set to high beam.

Battery Control System

Pub Date: 2020-01-09

Pub Number: US20200014231

The purpose of the present invention is to provide a battery control system which enables extending the communication range between a cell controller and a battery controller while keeping power consumption in the cell controller low and which is capable of ensuring communication reliability. In this battery control system, after transmitting a response request to the cell controller, the battery controller transmits to the cell controller a non-modulated wave having a power level lower than that of the response request, and the cell controller generates a response signal by performing amplitude-modulation on the non-modulated wave (see FIG. 6).

DISPLAY DEVICE

Pub Date: 2020-01-09

Pub Number: US20200013985

In a display device, an edge portion of a pixel electrode is modified. A valley is provided in an overcoat layer located below the pixel electrode. The edge portion of the pixel electrode is configured to be curved or bent onto the overcoat layer. As a result, the aperture ratio of the display device can be increased, and an image abnormality in the edge portion of the pixel electrode can be prevented.

VEHICLE ELECTRICITY STORAGE DEVICE

Pub Date: 2020-01-09

Pub Number: US20200010070

A vehicle electricity storage device includes a capacitor unit for supplying stored electric power to an electronically controlled system, and a microcomputer including a memory. The memory stores a plurality of thresholds (internal resistance limit values) different from each other. Each of the plurality of thresholds is to be compared with an electrical characteristic value (internal resistance value) related to the capacitor unit for determining a deterioration state of the capacitor unit. The each of the plurality of thresholds is stored in association with an identification ID for identifying the electronically controlled system. The microcomputer acquires the identification ID from the electronically controlled system. And the microcomputer selects, from the plurality of thresholds, a threshold associated with the identification ID acquired. Then the microcomputer determines the deterioration state of the capacitor unit by using the electrical characteristic value and the threshold selected.

METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE

Pub Date: 2020-01-09

Pub Number: US20200010490

A method of stabilizing imino-functional silane involving adding thereto at least one Brnsted-Lowry base to inhibit, suppress or prevent the addition reactions of the imino-functional silane with itself to form a imino- and amino-functional silane and the subsequent deamination reactions to form conjugated carbon-carbon double bond-containing imino-functional silanes and stabilized imino-functional silanes containing the at least one Brnsted-Lowry base.