Total 8897 patents for "2019-06-27"

TRANSPLANTATION EFFECT OF DOPAMINE NEURON ENGRAFTMENT BY CO-TRANSPLANTATION OF MIDBRAIN ASTROCYTES AND VM-NPCS

Pub Date: 2019-06-27

Pub Number: US20190194612

The present invention relates to: a cell therapeutic agent including ventral midbrain-derived astrocytes and dopamine neural progenitor cells; a method of treating a neurodegenerative disorder including administering a pharmaceutical composition comprising ventral midbrain-derived astrocytes and dopamine neural progenitor cells into a subject; and a method for differentiation into dopamine neurons, which includes preparing a mixture of ventral midbrain-derived astrocytes and dopamine neural progenitor cells and co-culturing or co-grafting the mixture. The co-grafting of ventral midbrain-derived astrocytes and dopamine neural progenitor cells (neural stem cells) improves the survival and differentiation of dopamine neurons and thus dramatically improves therapeutic outcomes in a neurodegenerative disorder including Parkinson's disease.

ANTI-OSTEOSARCOMA CAR-T DERIVED FROM THE ANTIBODY OI-3

Pub Date: 2019-06-27

Pub Number: US20190192573

The invention relates to chimeric antigen receptor (CAR) specific to p80 and CD146, vectors encoding the same, and recombinant T cells comprising the p80 or CD146 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a p80 or CD146 binding domain.

System and Method for Creating a Snapshot of a Subset of a Database

Pub Date: 2019-06-27

Pub Number: US20190196914

A system for creating a snapshot of a subset of a database stored as a plurality of segments in an address space, where the system includes a processor configured to determine from the segments, one or more source segments of the snapshot, and allocate, using a virtual memory creation unit for the snapshot, one or more snapshot segments within the address space, where the one or more snapshot segments are mapped to same physical memory addresses as the one or more source segments, and where the one or more source segments and/or the one or more snapshot segments are set to copy-on-write.

Intake Shield Assembly

Pub Date: 2019-06-27

Pub Number: US20190194967

An intake shield assembly for inhibiting a pool skimmer from being plugged includes a pipe that is extended into an intake of a pool skimmer thereby inhibiting objects from entering the intake. A pair of arms is provided and each of the arms is coupled to the pipe. Each of the arms abuts a wall of the pool when the pipe is extended into the intake thereby inhibiting the pipe from being drawn fully into the intake. An elbow is provided and the elbow is positioned in the intake of the pool skimmer. The elbow is fluidly coupled to the pipe when the pipe is extended into the intake. In this way the elbow inhibits objects from plugging the intake.

CASH PROCESSING SYSTEM, CASH PROCESSING METHOD, PORTABLE TERMINAL AND CASH PROCESSING MACHINE

Pub Date: 2019-06-27

Pub Number: US20190197813

A cash processing system capable of preventing erroneous operations by an operator during cash transfer processing and enabling the cash transfer to be executed efficiently. This system comprises a first cash processing machine for performing an outgoing cash transfer, a second cash processing machine for performing an incoming cash transfer, and a portable terminal. The portable terminal is equipped with a display unit, an operation unit for receiving input of cash transfer information, including cash information, and a communication processing unit. Upon receiving outgoing cash transfer information included in the cash transfer information from the portable terminal, the first cash processing machine pays out cash based on the outgoing cash transfer information. Upon receiving incoming cash transfer information included in the cash transfer information from the portable terminal, the second cash processing machine receives cash based on the incoming cash transfer information.

POWER GENERATING CELL

Pub Date: 2019-06-27

Pub Number: US20190198889

In a power generating cell, on a surface on a side opposite from an electrolyte membrane in an anode, there are provided an outer peripheral surface positioned on an outer peripheral portion of the anode, a central surface located more inwardly than an inner peripheral portion of a resin frame member, and a stepped portion connecting the outer peripheral surface and the central surface to each other. A height of the central surface from the electrolyte membrane is lower than that of the outer peripheral surface. A protruding end surface of an end linear protrusion is in contact with the central surface.

NETWORKED STORAGE REDUNDANCY SCHEME

Pub Date: 2019-06-27

Pub Number: US20190196900

A system and method for improved redundancy in storage devices are disclosed. The method includes receiving a first data block for writing to a storage device; writing the first block to a journal connected with the storage device; associating a first logical address of a group of logical addresses of the journal with a first physical address of the storage; associating the first physical address to an additional second logical address of the storage device, the second logical address not of the group of logical addresses of the journal; and disassociating the first physical address from the first logical address, in response to associating the first physical address with the additional second logical address.

DEGRADEABLE NASAL OSTIAL STENT

Pub Date: 2019-06-27

Pub Number: US20190192318

A polymeric stent having a length, an outer surface and a cross-section. A lumen passes through the entire length, the lumen having a surface forming an equivalent diameter in the polymeric stent. The polymeric stent includes a first aqueous-swellable, biocompatible and biodegradable composition (e.g., polymer) having a thickness. The aqueous-swellable and biodegradable polymer retaining structural integrity for at least 1 hours up to thirty days when swollen to between 15% and 500% of its dry diameter and kept moist by a moist aqueous environment. Barrier layers of biodegradable polymer(s) may be used to prevent migration of liquids into the lumen.

Self-Lubricating Rolling Bearing and Preparation Method Therefor

Pub Date: 2019-06-27

Pub Number: US20190194771

A self-lubricating rolling bearing is provided. The chemical compositions in the inner rings and the outer rings of bearing are 3.4-3.7% C, 2.7-2.9% Si, 0.3-0.5% Mn, 0.3-0.5% Cr, 0.05% S, 0.05% P, 0.03-0.045% Residual Mg, and the remainder Fe. The total percent of the chemical compositions is 100%. The material for the inner and outer rings of the rolling bearing introduced in the invention is austempered ductile iron (ADI). In the microstructure of ADI, the diameter of the graphite nodules is less than 0.02 mm, the number of graphite spheres per square millimeter is more than 400, and the microstructure of the metal matrix in the ADI can be showed clearly only when it is observed on the microscope with a magnification more than 500. Eventually, the self-lubricating rolling bearings are made from the ADI.

METHOD AND SYSTEM FOR TRADING FINANCIAL DERIVATIVES

Pub Date: 2019-06-27

Pub Number: US20190197625

Methods and system provided present information for trading of financial instruments and their derivatives, such as options trading, in an easily and intuitively understood manner. The system provides an intuitive interface to allow users to understand and manipulate complex trading and analysis on smartphones, tablets, and personal computers. The system has a date slider, a profit and loss chart, and a limit panel intuitively displayed and that move in conjunction with each other to allow traders too quickly and visually interpret information. The system combines both historical charts and a measure of the risk of a trade (a profit and loss chart) in a frame that shows a relevant range of future outcomes for the asset and time horizon chosen (a range of confidence), as well as the limit slider to define open and close limits.

OBJECT-ORIENTED REMOTE PROCEDURE CALLS FOR BROWSER APPLICATIONS

Pub Date: 2019-06-27

Pub Number: US20190196891

A system is provided for an application executed by a client to invoke a remote object method of a remote object of a remote object class that is hosted by a server. The application instantiates a proxy of a proxy class that includes a proxy member function with the same signature as the remote object member function. The application associates an object identifier with the proxy. The application invokes the proxy member function of the proxy. Under control of the invoked proxy member function, the application sends to the server an invocation request message that includes the object identifier that is associated with the proxy and an identifier of the remote object member function. The application relies on functionality provided by the browser without the need for the browser to access add-on functionality when executing the application.

INTERNET-BASED SEMICONDUCTOR MANUFACTURING EQUIPMENT HEALTH AND DIAGNOSTICS MONITORING

Pub Date: 2019-06-27

Pub Number: US20190196461

A system, apparatus and method for internet-based health and diagnostic monitoring of semiconductor manufacturing components include receiving health and diagnostic information and data from at least one component of a semiconductor manufacturing system, evaluating the received health and diagnostic information and data to determine if at least one of the at least one component of the semiconductor manufacturing system for which the health and diagnostic information and data was received is faulty, and if determined that at least one of the at least one component of the semiconductor manufacturing system is faulty, initiating a corrective action for the faulty component over the internet.

METHODS FOR GENERATING A GLUCOSE PERMEASE LIBRARY AND USES THEREOF

Pub Date: 2019-06-27

Pub Number: US20190194647

The present disclosure describes methods for generating microbial strains expressing a heterologous bacterial glucose permease gene that produce biomolecules of interest. In aspects, the disclosure provides novel bacterial strains, which express a heterologous bacterial glucose permease gene whose expression is controlled by a native Corynebacterium glutamicum promoter or a mutant promoter derived therefrom. Also provided herein are methods for producing a library of bacterial glucose permease genes using a promoter ladder comprising a plurality of promoters derived from Corynebacterium glutamicum.

MULTI-MATERIAL CONSTRUCTION OF GEARS

Pub Date: 2019-06-27

Pub Number: US20190193140

A method for fabricating an article that includes: providing a first workpiece component formed of a first steel material; joining a second workpiece component to the first workpiece component to form a workpiece, the second workpiece component being formed of a second steel material that is different from the first steel material; and forming a plurality of teeth on the workpiece, the teeth being wholly formed of the first steel material.

GAIN CALIBRATION AND CORRECTION IN RADIATION SYSTEM

Pub Date: 2019-06-27

Pub Number: US20190192106

Among other things, one or more techniques and/or systems for calibration of a radiation system to compute a gain correction(s) are provided. A calibration procedure is performed during which a portion of the detector array is shadowed by an object, causing the detector array to be non-uniformly exposed to radiation. A portion of a projection generated from the calibration procedure and indicative of radiation that did not traverse the object is separated from a portion of the projection indicative of radiation that did traverse the object, and a gain correction(s) is computed from the portion of the projection indicative of radiation that did not traverse the object (e.g., and is thus indicative of radiation that merely traversed air).

SYSTEM AND METHOD FOR REDUCING PULSATILE PRESSURE

Pub Date: 2019-06-27

Pub Number: US20190192835

A device for reducing pressure within a lumen includes a reservoir structured for holding a fluid therein, an injection port in fluid communication with the reservoir, a compliant body structured to expand and contract upon changes in pressure, and a conduit extending between and fluidly coupling the reservoir and the compliant body. The fluid may be a compressible or a noncompressible fluid.

LIGHTWEIGHT ELECTRIC EARTH DRILL

Pub Date: 2019-06-27

Pub Number: US20190195019

Disclosed is a lightweight electric earth drill including a mounting plate, a drill stem and an outer shell, a motor installed on the mounting plate and configured to drive the drill stem to rotate, a rechargeable battery configured to power the motor, and a controller configured to control the motor and electrically connected to the motor and the rechargeable battery. The lightweight electric earth drill is driven by the motor and has low noise, which causes less damage to health of the workers and does not disturb the residents around the construction site. The lightweight electric earth drill is powered by rechargeable battery or mains electricity without exhaust emission. The motor is controlled by the controller and rotates forwardly and reversely, enabling the drill bit to be pulled out after drilling the earth.

PREPARATION SYSTEM FOR THE PREPARATION OF WHITE ICE

Pub Date: 2019-06-27

Pub Number: US20190195544

A unit for the preparation of cold, purified and carbonated water. The unit comprises a connection for a water supply; an optional sterilisation unit, e.g. in the form of a unit comprising at least one water inlet and at least one hot water outlet for discharging purified water. Further, there is a cooling unit comprising at least one hot water inlet and at least one cold water outlet; a carbonation unit comprising at least one inlet for introducing carbon dioxide into the cold, purified water so as to prepare cold, purified and carbonated water; and a water outlet for the delivery of the cold, purified and carbonated water from the pre-module to a freezing unit of an ice-making unit.

PROCESSING METHOD FOR PHOTOVOLTAIC CELL AND STRING WELDING AND CURING DEVICE FOR PHOTOVOLTAIC CELL

Pub Date: 2019-06-27

Pub Number: US20190198690

The present disclosure provides a processing method for a photovoltaic cell and a string welding and curing device for a photovoltaic cell. The method includes step S1: plating both side surfaces of a monocrystalline silicon wafer; Step S2: forming a first electrode on one side surface of the plated monocrystalline silicon wafer; Step S3: forming a second electrode on the other side surface of the plated monocrystalline silicon wafer, to form a cell sheet; and Step S4: string welding a plurality of cell sheets and at the same time, curing the first electrode and the second electrode, by using a string welding and curing device for a photovoltaic cell. With the processing method provided by the present disclosure, the electrodes on the cell sheets can be cured while the cell sheets are string welded. It can save resources, shorten the processing time of the photovoltaic cell, and improve the production efficiency.

DISPLAY DEVICE, TEST CIRCUIT, AND TEST METHOD THEREOF

Pub Date: 2019-06-27

Pub Number: US20190197930

The embodiments of the present disclosure relate to a display device, a test circuit, and a test method thereof. More specifically, a display device may include a silicon substrate having a plurality of gate lines, a plurality of data lines, a plurality of sensing lines, and a pixel array on which a plurality of subpixels are arranged; a test circuit arranged on the silicon substrate, the test circuit configured to select at least one line of the plurality of data lines or the plurality of sensing lines, to convert a signal transmitted through the selected line into a digital signal, and to output test data; and a test pad unit configured to output the test data to a circuit outside the silicon substrate.

SEALING PROFILE FOR EMBEDDING INTO A MOULDING OF CURABLE MATERIAL

Pub Date: 2019-06-27

Pub Number: US20190195070

A sealing profile for embedding into a moulding of curable material, in particular a concrete or plastic moulding, and to a sealing arrangement comprising such a sealing profile. The object of the present invention is to provide a sealing profile for embedding into a moulding of curable material that can be anchored into the moulding in particular such that displacements of the seal in its seat occur to a significantly lesser extent, if at all, when installing or assembling the mouldings. The object is achieved by a sealing profile (1) with a profile region (2) having a profile region surface (4) which is directed towards the moulding (3) after embedding the sealing profile (1). The profile region (2) has, at least in a subregion (6), fibres (5) which are fixedly connected to the sealing profile (1) and extend beyond the profile region surface (4).

MALLEABLE PRESS FITTINGS

Pub Date: 2019-06-27

Pub Number: US20190195408

A cast body for a pipe fitting includes a first body end and a second body end disposed opposite from the first body end. The body defines an axis extending from the first body end to the second body end, an inner body surface defining a fitting bore that extends through the body, and an outer body surface spaced from the inner body surface at a predetermined wall thickness. At a first location on the axis, the inner body surface is a first distance and the outer body surface is a third distance from the axis, and at a second location on the axis that is proximate to the first body end, the inner body surface is a second distance from the axis that is greater than the first distance and the outer body surface is a fourth distance from the axis that is less than the third distance.

Systems and Methods for Facilitating Data Entry into Small Screen Electronic Devices

Pub Date: 2019-06-27

Pub Number: US20190196712

An input signal corresponding to an action other than a drag on any virtual keyboard causes an erroneous string having at least two characters with an incorrect character other than the last character to be displayed. A second input signal corresponding to a drag on a virtual keyboard triggers entry into an error correction mode. A first incorrect character is located, a corrected input is determined according to an angle and a slide direction of the first drag, and the layout and geometry of the virtual keyboard; the first incorrect character is replaced with the corrected input to provide and display a first corrected string. The replacement of the first incorrect character and the display of the first corrected string occur without input from any source external to the device other than the first and the second input signals.

CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS

Pub Date: 2019-06-27

Pub Number: US20190194254

In some aspects, the present invention provides cell-reactive compstatin analogs and compositions comprising cell-reactive compstatin analogs. In some aspects, the invention further provides methods of using cell-reactive compstatin analogs, e.g., treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ. In some aspects, the invention provides long-acting compstatin analogs and compositions comprising long-acting compstatin analogs. In some aspects, the invention further provides methods of using long-acting compstatin analogs, e.g., to treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ. In some aspects, the invention provides targeted compstatin analogs and compositions comprising targeted compstatin analogs. In some aspects, the invention further provides methods of using targeted compstatin analogs, e.g., to treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ.

FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS SUBSTITUTED WITH GUANIDINO GROUPS

Pub Date: 2019-06-27

Pub Number: US20190194226

Fused [1,2]Imidazo[4,5-c] ring compounds (e.g., imidzao[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridines) substituted on the fused ring with a group that contains a guanidine or substituted guanidine moiety, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are also disclosed.

INDIVIDUAL ENCRYPTION OF CONTROL COMMANDS

Pub Date: 2019-06-27

Pub Number: US20190199694

The present invention is directed to a method for efficiently and individually encrypting control commands, which makes it possible to encrypt supplied applications and to transmit them to an end device not only in an efficient but also in a particularly secure way.

AIR SEAL ATTACHMENT

Pub Date: 2019-06-27

Pub Number: US20190195079

A gas turbine engine includes a coupling and an air seal attachment. The annular coupling extends along a centerline and has coupling teeth that extend axially rearward. The annular air seal attachment includes an air seal at an axially rearward end and air seal attachment teeth at an axially forward end that extend axially forward to interlock with the coupling teeth such that the air seal attachment teeth and the coupling teeth alternate in a circumferential direction.

ASYNCHRONOUS SPEECH ACT DETECTION IN TEXT-BASED MESSAGES

Pub Date: 2019-06-27

Pub Number: US20190197103

Various embodiments are described herein that relate to communication systems that employ Natural Language Processing (NLP). More specifically, various embodiments relate to systems, methods, and interfaces for performing asynchronous speech act detection on text-based messages transmitted between used of a communication platform. Asynchronous speech act detection allows the content of the messages to be analyzed without interrupting the flow of communication. That is, the messages can be posted for viewing (e.g., to a chat room) and simultaneously transmitted to an NLP server for further analysis. The posted messages can subsequently be updated (e.g., by adding labels that are used for storing, searching, etc.).

ROTOR SUPPORT DEVICE, ROTOR, GAS TURBINE ENGINE, AND AIRCRAFT

Pub Date: 2019-06-27

Pub Number: US20190193842

A rotor support device includes a plurality of first electrodes, a plurality of second electrodes, a dielectric material, and at least one alternating-current power supply. The dielectric material is disposed between the plurality of first electrodes and the plurality of second electrodes. The at least one AC power supply is configured to apply an alternating-current voltage across the plurality of first electrodes and the plurality of second electrodes and induce flows of gas by causing dielectric barrier discharge between the plurality of first electrodes and the plurality of second electrodes. At least one of the plurality of first electrodes or the plurality of second electrodes is disposed apart from each other in a static system that is stationary with respect to a rotor provided in an aircraft. The static system is adjacent to the rotor.

MODEL ENSEMBLE GENERATION

Pub Date: 2019-06-27

Pub Number: US20190197395

A method of generating a model ensemble may be provided. A method may include training a base model including a plurality of layers. The method may also include generating a plurality of models for the neural network based on the base model. Each model of the plurality of models includes a plurality of layers. Further, the method may include modifying a layer of each of the plurality of models such that each model of the plurality of models includes a layer modified with respect to an associated layer of each of the base model and each of the other plurality of models. In addition, the method may include tuning each modified layer of the plurality of models.